Manchester City striker Sergio Aguero is returning to England after failing to recover from injury while on international duty.
The 24-year-old had originally been named in the squad for Argentina's 2014 FIFA World Cup qualifiers at home to Venezuela and away to Bolivia.
Aguero had been struggling with a knee injury and although his condition had improved, the team's fitness staff believe he would be better off missing out.
The striker wrote on Twitter: "My knee is better but the squad's physicians would rather have me be safe and stick with the treatments until it's completely healed.
"It's a pity to miss out on the national squad matches but I'll be cheering for Argentina from Manchester, while I finish the recovery."