Manchester United have already secured their place in the knockout stages of the competition, as a 3-1 win in Braga almost a fortnight ago made it four wins out of four so far.

And with his team looking to maintain their Premier League title challenge, Ferguson has opted to rest a number of senior names - including Paul Scholes, Ryan Giggs, Antonio Valencia and David De Gea - in favour of some of the club's younger players.

Goalkeeper Sam Johnstone and defender Tom Thorpe, who have yet to make a senior appearance for the Old Trafford side, have featured at Under-21 level for the club and are capped at England Under-19 level.

Squad: Goalkeepers: Sam Johnstone, Anders Lindegaard.

Defenders: Rafael, Alexander Buttner, Phil Jones, Tom Thorpe, Marnick Vermijl, Scott Wootton.

Midfielders: Michael Carrick, Davide Petrucci, Larnell Cole, Tom Cleverley, Darren Fletcher, Anderson, Nick Powell, Ashley Young, Ryan Tunnicliffe.

Strikers: Javier Hernandez, Joshua King, Danny Welbeck, Federico Macheda.

Meanwhile, United fans have been urged to show caution throughout their stay in Istanbul.

The Foreign Office have released a string of guidelines amidst concerns there could be a repeat of United’s 1993 trip to play the Turkish side, which was marred by violence off the pitch.

A total of 178 United fans were arrested on that visit after a number of clashes away from the stadium, including one which smashed up an Istanbul hotel.

The match itself was not free of ugly scenes either, with a brawl breaking out between the two sets of players.

United players were infamously greeted with 'Welcome to Hell' banners and a vociferous reception from local fans after their arrival in Turkey before they were defeated on away goals.