Both players picked up knocks last weekend, with Ibrahimovic suffering a calf injury during the warm-up prior to the 4-1 win over Athletic Bilbao while Pique sustained a thigh problem during the match.

Ibrahimovic has not recovered in time for 'El Clasico' and has been omitted from Pep Guardiola's 19-man squad for the trip to the Bernabeu, but Pique has been included after training normally with his team-mates today.

Also missing is left-back Eric Abidal, who limped out of Tuesday's Champions League victory over Arsenal after aggravating a thigh injury.

Barca and Madrid are locked on 77 points at the top of the league table with eight games remaining in the season.