Inter go into the encounter against the Eternal City outfit on the back of a 0-0 home draw against Manchester United in the opening leg of their Champions League last-16 match.

Despite the result, coach Jose Mourinho is convinced his players will come up with the goods in the return match at Old Trafford on March 11.

"The result doesn't disturb me," said Mourinho. "It would have been easier to travel to Manchester having scored a goal.

"This result gives us hope and I am confident that my team can go to Old Trafford and score."

The Nerazzurri will attempt to make it four league wins in a row and extend their nine-point advantage over second-place Juventus when they entertain sixth-place Roma.

Luciano Spalletti´s Roma lost 1-0 at Arsenal in their midweek Champions League tie and will face a challenge as they look to end Inter´s unbeaten run at home this season.

With 13 games left to play, Juventus and AC Milan will be hoping for a Roma victory as they attempt to narrow the gap with Inter.

Juve entertain Napoli in Turin looking to bounce back from Wednesday´s 1-0 Champions League setback at Chelsea that complicated their European ambitions.

Claudio Ranieri´s men expect to collect three points against a Napoli side that have not won since their 1-0 triumph against Catania on January 11.

AC Milan make the journey to Genoa to meet Sampdoria with the good news that Brazil playmaker Kaka has recovered from a foot injury and will be available for selection. The Rossoneri are two points behind Juve.

Fourth-place Fiorentina will be looking to extend their five-game unbeaten run when they make the journey south to meet rock-bottom Reggina.

The Florence-based outfit will have to do without their top scorer, Alberto Gilardino, who serves a one-match ban.

Genoa meet Siena in Tuscany in buoyant mood having clinched their fourth win on the road this season in last weekend´s 1-0 triumph at Napoli.

That win left Genoa one point behind Fiorentina and one clear of Roma.

Cagliari take on relegation-threatened Torino looking to continue their solid home form.

Massimiliano Allegri´s side are seventh in the Serie A standings and will fancy their chances against Toro having collected 26 of their current 37 points at the Sant´Elia stadium.

Atalanta will have to overcome the absence of injured captain Cristiano Doni when they meet strugglers Chievo.

Palermo lost their third game at La Favorita this season in last weekend´s 2-0 loss against Juventus and will look to return to winning ways when they entertain Catania.

Lazio host Bologna on Saturday looking for their first win in the Italian capital since December 20.

Relegation-threatened Lecce will be desperate to avoid their fourth consecutive defeat when they travel to Friuli to meet Udinese.