An Alessandro Del Piero-inspired Juventus ended Inter Milan's unbeaten home record in Serie A this season to throw the title race wide open.
After a goalless first half, Mauro Camoranesi put the visitors ahead in the 49th minute before a fine assist from Del Piero set up David Trezeguet to volley in Juve's second in the 63rd minute.
Del Piero had chances to add a third, and it was a nervous end for the Bianconeri when Maniche grabbed a consolation six minutes from time before hitting the post in stoppage-time.
But Inter could not find an equaliser, leaving the Scudetto up for grabs after 10-man Roma beat Empoli 2-1 to move within four points of the leaders with eight games to go.
Fiorentina saw off 10-man Lazio 1-0 to maintain their four-point cushion in the final Champions League spot, while AC Milan won by the same score at Torino.
Sampdoria salvaged a 1-1 draw against basement boys Cagliari, while Udinese secured a 2-0 win over Livorno.
Genoa claimed claimed a 3-2 win at Palermo, Atalanta and Catania played out a 0-0 draw, Reggina drew 1-1 with Napoli, and Siena beat Parma 2-0.
Del Piero had chances to add a third, and it was a nervous end for the Bianconeri when Maniche grabbed a consolation six minutes from time before hitting the post in stoppage-time.
But Inter could not find an equaliser, leaving the Scudetto up for grabs after 10-man Roma beat Empoli 2-1 to move within four points of the leaders with eight games to go.
Fiorentina saw off 10-man Lazio 1-0 to maintain their four-point cushion in the final Champions League spot, while AC Milan won by the same score at Torino.
Sampdoria salvaged a 1-1 draw against basement boys Cagliari, while Udinese secured a 2-0 win over Livorno.
Genoa claimed claimed a 3-2 win at Palermo, Atalanta and Catania played out a 0-0 draw, Reggina drew 1-1 with Napoli, and Siena beat Parma 2-0.
Copyright (c) Press Association
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