Ola Toivonen struck twice in the second period to set up the victory while Orlando Engelaar added a third at the death.

Milan Kopic pulled Heerenveen level just after the hour mark but PSV's greater class told as the match wore on.

Heracles Almelo made a fine start to their campaign with a comfortable win over Willem II, who look set for another season of struggle after surviving a relegation play-off in May.

Marko Vejinovic opened the scoring for Heracles in just the second minute before a second-half double from Glynor Plet made the result safe for last season's sixth-place finishers.

A largely uninspiring season opener between NEC Nijmegen and VVV Venlo was settled five minutes into the second period as Ramon Zomer's header secured all three points for home side NEC.

De Graafschap began life back in the top division with a bang as they crushed fellow top-flight new boys Excelsior 3-0. Rydell Poepon opened the scoring in the eighth minute and Muslu Nalbantoglu added a second on the hour mark.

Steve De Ridder made it three with six minutes left as last season's Eerste Divisie champions ran out easy winners.