Defender Bailey Wright replacing injured Trent Sainsbury is the only change made by Socceroos coach Graham Arnold to his squad for upcoming World Cup qualifiers against Nepal and Taiwan.

Sainsbury has been replaced by Bristol City's Wright in the 23-man squad, which is otherwise the same as that named for last month's qualifying opener against Kuwait.

The 27-year-old, who has recently moved to Israeli club Maccabi Haifa after being frozen out at Dutch giants PSV Eindhoven, has been placed on stand by with Arnold saying his omission is a precautionary one.

"He probably could've played in the Nepal game but he hasn't had many training minutes and many game minutes of the last few weeks," Arnold told Fox Sports.

Wright has made 23 appearances for the Socceroos and played a full 90 minutes in June's 1-0 friendly loss to South Korea.

Captain Mark Milligan has been named having withdrawn before the 3-0 win over Kuwait due to injury.

Sainsbury's absence means a debut looms large for Fleetwood Town defender Harry Souttar - the only uncapped player in the squad.

The Scottish-born 20-year-old didn't feature against Kuwait but Arnold hinted strongly he could make his international bow next Thursday against Nepal in Canberra.

"I think that the Australian fans will love Harry Souttar," Arnold said. "The size of him is pretty scary straightaway but he's a very, very good footballer."

The impact on the opening round of the A-League is minimal with just three domestically-based players picked.

Champions Sydney FC are most heavily affected and will have to face Adelaide United next Friday in their season-opener without fullback Rhyan Grant or goalkeeper Andrew Redmayne.

Melbourne City will take on cross-town rivals Melbourne Victory on October 12 without in-form striker Jamie Maclaren, who'll be vying with Adam Taggart for a starting role up front for the Socceroos.

With Tom Rogic still finding full fitness after his knee injury last season, the Celtic midfielder has been given a leave pass by Arnold to get married.

With experienced European-based stars Mat Ryan, Mathew Leckie and Aaron Mooy all included, Arnold is confident he's picked his strongest available squad for the clashes with the Group B minnows.

"That's our best squad that's available," Arnold said.

"Rogic is coming back slowly ... he wasn't ready for September or this camp.

"Daniel Arzani is back on the pitch. He's playing in the reserve grade at Celtic. He will play for the Olyroos in Qatar in this FIFA window.

"Martin Boyle is nearly back so he's in good shape now.

"That is the squad that is probably our A-squad."

The Socceroos will assemble in Canberra on Monday before taking on Nepal at GIO Stadium on Thursday.

They then travel to take on Taiwan in Kaohsiung on October 15.

Nepal started their campaign with a 7-0 thrashing by Kuwait but rebounded to post a 2-0 win over Taiwan, who are bottom of the group having lost their first two matches.

SOCCEROOS SQUAD TO PLAY NEPAL AND TAIWAN:

Mustafa Amini, Aziz Behich, Brandon Borrello, Milos Degenek, Apostolos Giannou, Craig Goodwin, Rhyan Grant, Ajdin Hrustic, Jackson Irvine, James Jeggo, Mitchell Langerak, Mathew Leckie, Massimo Luongo, Awer Mabil, Jamie Maclaren, Mark Milligan, Aaron Mooy, Andrew Redmayne, Mathew Ryan, Brad Smith, Harry Souttar, Adam Taggart, Bailey Wright.