United host relegation-battling Blackpool at home having already clinched the title, and it had been suggested Sir Alex Ferguson would rest his star players ahead of next week's Champions League final - potentially putting the other four clubs in the mix at the foot of the table - Wolves, Blackburn, Birmingham and Wigan - at a disadvantage.

The Premier League has only ever twice imposed punishments in regard to its rule on fielding weakened teams - ironically against two clubs potentially affected this time in Blackpool and Wolves - and Scudamore says he is confident it will not be a factor this weekend.

"I absolutely know that Manchester United will pick a team to go out and win that game," Scudamore told BBC Sport.

"As far as weakened teams are concerned, the Premier League has only ever applied the rule twice when it's been an extreme case and somebody has changed all 10 outfield players and then the week after, gone back and changed the 10 back again.

"That's not going to happen so I absolutely expect on Sunday that the teams, whoever is put out, will be out to win."

Scudamore said it was an accepted "quirk of the fixture list" that by the end of the season, some teams are playing against others who no longer have much to play for, but said the professionalism of the league made it a non-factor.

"I don't need to remind Manchester United or anybody else of their responsibilities," he said. "They are professional football clubs and professional managers. I wouldn't dare do that."

Meanwhile, Scudamore described the FA's decision to abstain in the FIFA presidential election as "disappointing" but said he could not criticise the board.

"I'm disappointed but not critical," he said.

"At the end of the day, it is a shame that the English FA, with all its proud history and involvement in FIFA, can't bring itself to vote for a candidate in a presidential election.

"It's far too late to put anybody else up - I've seen some press reports today that we should have put up a third candidate but the nominations closed at the end of April.

"But am I critical of the FA for reaching that decision? No. They are sat there as a democratic board and it would have weighed heavily on them to abstain, but I couldn't criticise them for it.

"It's one of the options open to them and I couldn't criticise them as they have been put in a very difficult position."

The Premier League have been calling for a change at FIFA, but Scudamore denied that necessarily meant they wanted to see president Sepp Blatter voted out.

"People have read that to mean we should be supportive of (Mohamed) Bin Hammam," he said.

"What we've always said is that we believe there should be a manifesto approach where people are voted for on the basis of an agenda, but it's not a prerequisite that it's necessarily anti-Blatter.

"But we don't have a vote. The Premier League is not a full member association of FIFA. But clearly we believe there is some change required and we've always said that."