The Gunners, who beat Shakhtar Donetsk 5-1 on Tuesday in the Champions League, head to Manchester City in the Barclays Premier League on Sunday knowing victory would put them above Roberto Mancini's team on goal difference.

"I see a real opportunity to have great achievements this season - we have the spirit, talent, hunger and desire," said Wenger.

"I do not say there are no weaknesses - we are conscious of that - but we work very hard.

"We will go for every single competition this season with every resource we have and we will give absolutely everything."

Leaders Chelsea could move provisionally five points clear at the summit if they overcome Wolves at Stamford Bridge on Saturday.

Striker Didier Drogba looks set to return to lead the Blues' attack after a virus, but midfielder Frank Lampard (hernia) and centre-back Alex (thigh) are not yet ready to play.

Manchester City could move top of the pile if Mick McCarthy's side, who lie in the relegation zone along with Liverpool and West Ham, manage a shock win at the home of the champions.

Manchester United will be glad to focus on on-field matters after a week of headlines over Wayne Rooney expressing his desire to leave Old Trafford.

Sir Alex Ferguson's fourth-placed side visit Stoke on Sunday.

Scotland midfielder Darren Fletcher has led the defence of his United team-mates against Rooney's allegations that they are not good enough for him.

"I am confident we can win trophies," he said.

"We have a lot of exciting, young players, who are getting better every day. You can see in training that they are improving all the time."

Fifth-spotted Tottenham host Everton in the weekend's first game, knowing their opponents will be much more rested for the Saturday lunchtime kick-off at White Hart Lane.

While David Moyes' 11th-placed Toffees have had all week to prepare following last weekend's Merseyside derby victory, Spurs will have had little more than two days to recover from last night's 4-3 Champions League defeat at Inter Milan.

Wales winger Gareth Bale, who netted a stunning hat-trick at the San Siro last night, has assured Tottenham fans he has no intention of quitting the club.

He said in the Evening Standard: "I don't read into anything said about me. I am just happy playing week in, week out for Tottenham and learning my football here.

"I am happy and I want to keep playing.

"I don't take any interest in what is written about me because I think it's best to keep your feet on the ground, go to training and learn and also learn in the games every week."

Moyes' side had a shaky start to the new season but will head to the capital not only well rested but full of confidence following three clean sheets on the bounce.

Also on Saturday, West Ham host Newcastle looking to lift themselves off the foot by securing their second win of the season.

If Avram Grant's team and Wolves both avoid defeats, Liverpool will be bottom of the standings by the time they kick off against Blackburn on Sunday.

Reds boss Roy Hodgson left several first-teamers on Merseyside for tonight's Europa League clash in Napoli, prioritising the vital league game this weekend.

"For me it was, quite simply, a priority," said Hodgson.

"After our very poor start to the season and bad results, if we had to make a sacrifice within the team in one game or another which game do you make it?"

In other games on Saturday, Birmingham take on Blackpool, Sunderland host Aston Villa, West Brom play Fulham and Wigan face Bolton.