John Kosmina's team, officially under the guidance of assistant Luciano Trani while Kosmina studies for his coaching A-Licence, overcame Bunyodkor on the way to the 2008 final, which they lost to J.League giants Gamba Osaka.

The A-League outfit will welcome David Carney's Bunyodkor, who they beat once and also drew against in the group stages, to Hindmarsh Stadium for the first leg on September 19.

If the Reds are again victorious, they will face the winner of the Ulsan-Al Hilal last-eight clash.

In further good news for Adelaide, they will host the final - to be played on either November 9 or 10 - if they win their way through.

On the other side of the draw, big-spending Chinese Super League outfit Guangzhou Evergrande face two-time Asian champions Al Ittihad.

Marcello Lippi's side make the trip to Saudi Arabia for the first leg on September 19 before hosting the return leg in early October.

Awaiting the winner in the last four are either Sepahan or Al Ahli.

Quarter-final draw:
Al Ittihad v Guangzhou Evergrande
Sepahan v Al Ahli
Adelaide United v Bunyodkor
Ulsan Hyundai v Al Hilal