Jose Mourinho's men travel north in the week commencing September 24, while last season's beaten finalists Arsenal face Newcastle in one of several all-Premier League ties.

Blackburn play Birmingham, Reading are at home to Liverpool, Tottenham face Middlesbrough and Fulham meet Bolton in other all top-flight ties, while Manchester United are at home to Championship leaders Coventry, West Ham face Plymouth at Upton Park and Manchester City have home advantage against Norwich.

Premier League clubs on their travels include Everton at Sheffield Wednesday and Portsmouth at Burnley.

Giantkillers Morecambe's reward for knocking out Preston and Wolves is another trip to face Championship opposition, Sheffield United, while the winners of the abandoned tie between Nottingham Forest and Leicester will visit Aston Villa, whose boss Martin O'Neill played for the former and managed the latter.

The east midlands rivals will replay their game on September 18 after Foxes defender Clive Clarke collapsed during the original game at the City Ground.

Luton's reward for beating Sunderland, meanwhile, is a home tie against Charlton.

The full draw:

Blackburn v Birmingham

Reading v Liverpool

Manchester United v Coventry

Tottenham v Middlesbrough

Hull v Chelsea

Blackpool v Southend

West Ham v Plymouth

Arsenal v Newcastle

Luton v Charlton

Manchester City v Norwich

Sheffield United v Morecambe

Sheffield Wednesday v Everton

Fulham v Bolton

Burnley v Portsmouth

Aston Villa v Nottingham Forest or Leicester

West Brom v Cardiff

:: Ties to be played week commencing September 24.