Strikes from Cuauhtemoc Blanco, Omar Bravo and Andres Guardado saw Hugo Sanchez's side overcome an early goal from Sebastian Abreu and repeat their performances of 1997 and 1999.

Uruguay were on the offensive straight away as only 60 seconds into the game Abreu shot narrowly wide before Jorge Fucile's effort was well stopped by Mexican keeper Guillermo Ochoa.

Ecuadorian referee Mauricio Reinoso turned down what looked like a clear penalty after defender Diego Lugano's challenge on Bravo after 18 minutes and Uruguay then immediately went ahead when Abreu headed home Maximiliano Pereira's cross.

But Mexico drew level in the 35th minute as Lugano was not so lucky second time around when he was shown a red card for elbowing Nery Castillo inside the area and Blanco equalised from the spot.

Mexico improved after the break and Blanco went close to giving his side the lead after 53 minutes but fired just wide.

Uruguay goalkeeper Fabian Carini then produced a good save to keep out Jaime Lozano's shot from the edge of the area before Bravo gave Mexico the lead when he beat the Internazionale stopper from outside the box.

Oscar Tabarez immediately brought on Fabian Canobbio and Vicente Sanchez to give Uruguay more of an attacking threat but Mexico put the result beyond doubt fifteen minutes from the end as Guardado's long-range effort found the back of the net via the underside of the bar.