Marko Pantelic opened the scoring for the hosts after 36 minutes while Sebastian Bartolini's dismissal after an hour for a second bookable offence was a further blow to Asteras' hopes.

David Fuster hit Olympiacos' second just a minute later before a Sokratis Fitanidis own goal completed the scoring after 72 minutes.

Adrian Bastia became the second Asteras player to see red when he committed a second bookable offence a minute from time.

Olympiacos have now won three of their opening four games and lead the way by a point from second-placed Panathinaikos, who were 2-1 winners over Panionios.

Sotiris Ninis hit Panathinaikos' first goal after 44 minutes before Kostas Katsouranis (63) made it 2-0.

Bennard Kumordzi pulled a goal back for the visitors in stoppage time while Ninis' night turned sour when he picked up a second yellow card at the death.

Atromitos picked up their first three-point haul of the campaign with a 2-1 victory over winless Panseriakos, despite ending the game with nine men.

Henri Camara (21) and Emanuel Perrone (30) had the hosts firmly in charge of the match but the dismissal of Lucas Favalli for a second booking on the stroke of half-time gave hope to Panseriakos.

The rock-bottom visitors pulled a goal back through Georgios Georgiadis after 66 minutes but failed to find an equaliser against their under-strength opponents, who also lost Evangelos Nastos to a straight red card in injury time.