Lecce's David Di Michele and Stefano Ferrario scored either side of strikes from Klose and Lorik Cana for the Rome outfit as the hosts looked set for a point in the week they sacked Eusebio Di Francesco and replaced him with Serse Cosmi.

But Klose had the final say with an 87th-minute winner that ensured Lecce remain bottom and put Lazio into second, a point behind Juve having played a game more.

Inter Milan vaulted from the fringes of the relegation zone into the top 10 of the congested league table with a 2-0 win at home to Fiorentina.

Former Viola striker Giampaolo Pazzini gave Claudio Ranieri's side the lead four minutes before the break, with Yuto Nagatomo adding the second after 49 minutes.

Palermo missed the chance to climb to fifth as they went down to a surprise 1-0 defeat at home to Cesena, who nevertheless remain inside the relegation zone after only their third win in 14 games this season.

Adrian Mutu scored the winner after 63 minutes, while seconds later Palermo were reduced to 10 men following the dismissal of Ezequiel Munoz for a second yellow card.

Goals from Marco Rossi and Rodrigo Palacio helped Genoa claim their first away win since September as they saw off Siena 2-0 at the Stadio Artemio Franchi.