Newcastle midfielder Abdoulaye Faye headed Senegal into the lead midway through the first half but Manucho, who agreed a three-and-a-half-year deal at Old Trafford last month, struck with a close-ranger header in the 50th minute before scrambling in a second 17 minutes later.

Flavio Amado added the third goal 12 minutes from time to put Angola in a strong position in Group D.

First-half goals from Brazil-born Francileudo Dos Santos (two) and Chaouki Ben Saada gave Tunisia a comfortable 3-1 victory over South Africa in Group D's other match.

Everton midfielder Steven Pienaar's shot was deflected in by team-mate Katlego Mphela with two minutes to go for South Africa, but it was scant consolation for the 2010 World Cup hosts.