Adelaide United have bundled Melbourne Victory out of the FFA Cup, while Heidelberg United progressed after a dramatic penalty shootout over Sydney United on Wednesday.
The Reds crushed Victory courtesy of three second-half goals, after a goalless first-half where Taylor Regan's crunching tackle on Mitch Austin was the major talking point at Marden Sports Complex.
South Melbourne were far too good for 10-man Sorrento at Lakeside Stadium, triumphing 4-1 with Nick Epifano netting a double.
Gold Coast City triumphed 1-0 over fellow NPL Queensland opponents Moreton Bay United in extra-time at Wolter Park.
Newly crowned NPL Victoria premiers Heidelberg United reached the quarter-finals after a dramatic 4-3 penalty shootout win over Sydney United 58 at Edensor Park.
Adelaide United 3 (Absalonsen 53', Blackwood 66', Konstandopoulos 89') Melbourne Victory 0
The Reds progressed with Danish winger Johan Absalonsen opening the scoring with a thumping strike shortly after the interval.
Adelaide doubled their advantage when Rhys Williams handballed inside the box, with George Blackwood converting the spotkick.
Nathan Konstandopoulos rounded out the scoring with the best goal of the night, curling the ball into the top corner from outside the box.