Although an injury-hit Glory looked slightly vulnerable heading into the encounter, McBreen helped ease some of the worries within the first minute as he fired home past Danny Vukovic.

McBreen doubled the tally in the 12th minute and despite Central Coast gaining control of possession, Andrija Jukic flicked in the third just before the break.

Adam Kwasnik pulled one back within four minutes of the re-start but Central Coast struggled to hit the target from there on as the Mariners lost just their second game to the Glory since the new competition began.

Perth's third win in a row sees Lawrie McKinna's men lose any mathematical chance of making the finals this season with two games remaining.

But Brisbane's surprise win over Sydney on Saturday night means the fourth-placed Glory are not assured of making the play-offs just yet.

Perth may be six points clear of the Roar with a substantially better goal difference, but the Brisbane side can't quite be counted out as they play Perth in the final round.

Despite coming into the game under an injury cloud, McBreen shrugged off any concerns within 48 seconds of the kick-off as the former Fury man scored Glory's fastest A-League goal.

A hopeful long-punt forward from Chris Coyne was fumbled by Mariners defender Chris Doig, allowing McBreen the chance to take possession and slot it home.

It only got worse for the Mariners 10 minutes later as McBreen doubled the advantage.

Mariner Andrew Clark appeared to have a long ball from Adriano Pellegrino covered but the midfielder didn't count on a determined effort from Scott Neville, who pressured Clark into going to ground in a tangle of legs close to the goal-line.

First to his feet, Neville crossed into the box for another McBreen finish, his fourth goal in four matches since heading west from North Queensland.

Central Coast had the chance to pull one back in the 25th minute when Glory stopper Aleks Vrteski, deputising for the injured Tando Velaphi, flapped at a header from Alex Wilkinson, but Pellegrino was on the goal-line to hook it away.

Despite being two down the Mariners were enjoying a good spell of possession and Pedj Bojic came within inches of the upright from a free kick.

But Glory added another in the shadows of half-time from a corner as Andy Todd sent a bouncing ball forward, allowing Jukic to get a toe to it and flick it in for his first Glory goal.

Any complacency from the hosts was eradicated within four minutes of the re-start as half-time Mariners substitute Kwasnik pulled one back, tapping the ball home after Nik Mrdja nodded against the post from a Brad Porter cross.

Another Mariners substitute in Nicky Travis forced Vrteski to tip around the post on the hour but his effort lacked venom and for the most part Central Coast, for all their huff and puff, lacked the killer ball into the area that would cut through Perth's back four.

A header from Mrdja went past the upright in the 73rd minute from a Travis cross but that was the best of the chances before the Glory stepped up the intensity once again in the last 10 minutes as Jukic saw a low shot from outside the area slide narrowly wide.